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1985: The first heart transplant is carried out in Medellin; it is, besides, the first one to be made in Colombia.
1995: Medellin's metro starts working, the first and so far the only one in Colombia
1888: The Mining School, which had great importance in the preparation of the ruling class in the first decades of the 20th century, is founded.
1972: The construction of Coltejer building, a symbol of the city, is completed
1924: Junin Teather is inaugurated.
1921: The tramway starts operating
1919: Bolivar Teather is inaugurated
1903: Circo Teatro Espana is founded
1916:The construction of San Vicente de Paul Hospital is started
1914: The Antioquia railway gets to Medellin
1932: Aviation field Las Playas is opened
1881: Museo de Zea, now Museo de Antioquia is founded
1541: Jeronimo Luis Tejelo discovers the Aburra Valley
1874: Francisco Javier Cisneros starts works for the Antioquia railway
1826: Medellin is proclamed the capital of Antioquia.
1819: General Jose Maria Cordova frees Antioquia from the Spanish yoke once and for all.
1813: Governor Juan del Corral proclamais the absolute independence of Antioquia from the Spanish monarchy.
1803: The construction of the Franciscan Convent, the seed of today's Universidad de Antioquia is started
1675: The royal letters patent arrive, turning the Ana place into the village of Nuestra Senora de la Candelaria.
1646: The Ana place, where Berrio Park is standing today, is founded.
1615: Francisco Herrera y Campuzano founds the town of San Lorenzo, where El Poblado stands today.
1785: Visitador Antonio Mon y Velarde arrives in Medellin, and he makes important transformations to the city.
1875: The construction of the Metropolitan Cathedral is started.
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2004: The Metrocable system, a cable-car network used as public transport, starts operations
•The IDB meeting was held in March 2009 in Plaza Mayor.
•Celebrating South American Games, sports remodeling units.
•Opening of the Park explores the December 8.
•Digital Medelln Award winner at the V Latin American Digital Cities. AHCIET.
•Was institutionalized in Medellin International Festival of Tango.
•In March, the integration is performed Exhibition and Convention of Medellin SA and the International Convention Centre Ltd, Plaza Mayor Medellin SA born
1575: Gaspar de Rodas is the first Spaniard to settle down in the valley.