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After entering the body the virus makes its way into the lungs and the lymph nodes. Once there, it starts the lytic cycle and begins to reproduce.
Smallpox
The initial symptoms of smallpox, 7 to 17 days after exposure, include the acute onset of fever, chills, headache, nausea, vomiting and severe muscle aches.
During this time, the infected person feels fine and is not contagious. The symptoms of smallpox begin with high fever, head and body aches, and sometimes vomiting.
Originated in Africa and then spread to India and China thousands of years ago. The first recorded smallpox epidemic was in 1350 BC during the Egyptian-Hittite war.
On average this takes about 12 days and is called the incubation period. At the end of 12 days, the virus moves into the bloodstream
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Collins., M. (2001, October 9). Bioterrorism. Retrieved from http://web.ebscohost.com/src/detail?vid=3&hid=105&sid=8e0b54f5-3647-4940-8751-56214f547b7b%40sessionmgr110&bdata=JnNpdGU9c3JjLWxpdmUmc2NvcGU9c2l0ZQ%3d%3d#db=ulh&AN=32V4193453712
(2000, September 12). Smallpox disease overview. Retrieved from http://www.bt.cdc.gov/agent/smallpox/overview/disease-facts.asp
(2003, August 14). Smallpox. Retrieved from http://www.historyforkids.org/learnscience/medicine/smallpox.htm
(2001, september 11). Smallpox. Retrieved from http://kidshealth.org/teen/infections/skin_rashes/smallpox.html#
